| Target Molecule | Acetyl Octapeptide-3 (Snap-8) |
| Synonyms | Snap-8, Acetyl Glutamyl Heptapeptide-3, Ac-EEMQRRAD-NH₂, N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp |
| CAS Number | 868844-74-0 |
| Sequence (3-Letter) | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂ |
| Sequence (1-Letter) | Ac-EEMQRRAD-NH₂ |
| Molecular Formula | C₄₁H₇₀N₁₆O₁₆S |
| Molecular Weight | 1075.16 |
| Service Category | Custom Synthesis / Cosmetic Peptide R&D |
| Synthesis Purity | Customizable (e.g., ≥95%, ≥98%, ≥99% by HPLC) |
| Appearance | White to off-white powder |
| Counter Ion | Acetate (TFA-free available) or Custom Options |
| Synthesis Technology | Solid-Phase Peptide Synthesis (SPPS) |
| Modification Options | Isotopic labeling, specific counter-ions, alternate N-terminal protections |
| Available Scale | Milligram (R&D) to Kilogram (Commercial Manufacturing) |
| Analytical Data | Comprehensive COA, HPLC, MS provided per batch |
| Usage | Raw material synthesized strictly for laboratory research, cosmetic formulation R&D, and industrial manufacturing. Not a finished drug. |
Snap-8 (Acetyl Octapeptide-3, CAS 868844-74-0) is an eight-amino-acid synthetic peptide featuring an N-terminal acetyl group and a C-terminal amide. It represents an elongated structural analog of Acetyl Hexapeptide-8 (Argireline). We synthesize this specific sequence as a high-purity raw material for structural research and cosmetic formulation development.
We utilize optimized solid-phase peptide synthesis (SPPS). This platform ensures highly efficient amino acid coupling—precisely managing the extended octamer sequence—and strict control over deletion impurities, yielding batches that meet rigorous HPLC purity specifications.
Yes. While the standard structure requires specific N-terminal acetylation, our modification services can add targeted isotopic labels, specific counter-ions (such as TFA to acetate conversions), or alternate terminal protections to suit specific physical chemistry requirements.
Our infrastructure transitions seamlessly from milligram-scale laboratory batches to kilogram-scale commercial production. We maintain rigorous batch-to-batch consistency essential for industrial-scale cosmetic formulation.
We serve as a strategic technical partner. Our team assists with sequence stability testing, impurity profiling, and the provision of complete analytical documentation to accelerate downstream formulation projects.
Snap-8, the trade name for Acetyl Octapeptide-3 (sequence Ac-EEMQRRAD-NH2), is a synthetic octapeptide developed as an extended analog of Argireline. Synpeptide provides comprehensive synthetic solutions for this target molecule, leveraging our technical expertise to support industrial formulation development and cosmetic R&D.
Through our established peptide synthesis platform, we achieve efficient coupling of the octamer sequence via optimized Solid-Phase Peptide Synthesis (SPPS). We strictly control impurity profiles and sequence deletions during manufacturing, ensuring the final Snap-8 material meets exact purity specifications (routinely ≥98% via HPLC). This rigorous process control guarantees the batch-to-batch reproducibility required for both early-stage research and late-stage commercial formulation.
The baseline structure of Snap-8 requires N-terminal acetylation and C-terminal amidation. Beyond these standard parameters, we offer extensive peptide modification services. Formulators can request specific counter-ion exchanges to adjust solubility profiles, targeted isotopic labeling for tracking studies, or alternate terminal modifications. These structural adjustments enable researchers to precisely tune the molecule's physical properties for advanced delivery systems.
Scaling a peptide from benchtop research to commercial application demands stable manufacturing protocols. We facilitate efficient large-scale peptide synthesis for Snap-8, managing the transition from milligram screening batches to kilogram-scale production. Our large-scale infrastructure ensures a continuous, reliable supply chain for global cosmetic manufacturers, supported by complete analytical documentation including COA, MS, and HPLC data for every delivered batch.
We function as a technical extension of our clients' teams, providing one-stop peptide formulation support. Our engineers assist clients in stability testing, degradation profiling, and identifying optimal handling conditions for Snap-8 in various matrices. By delivering precise analytical data alongside high-purity synthetic capacity, we enable R&D teams to execute complex formulation projects efficiently and confidently.
