| Target Molecule | Pentapeptide-3 (Vialox) |
| Synonyms | Pentapeptide-3V, Gly-Pro-Arg-Pro-Ala-NH₂, Pentapeptide-3 diacetate |
| CAS Number | 135679-88-8 (diacetate salt: 725232-44-0) |
| Sequence (3-Letter) | H-Gly-Pro-Arg-Pro-Ala-NH₂ |
| Sequence (1-Letter) | GPRPA-NH₂ |
| Molecular Formula | C₂₁H₃₇N₉O₅ |
| Molecular Weight | 495.58 |
| Service Category | Custom Synthesis / Cosmetic Peptide R&D |
| Synthesis Purity | Customizable (e.g., ≥95%, ≥98%, ≥99% by HPLC) |
| Appearance | White to off-white lyophilized powder |
| Counter Ion | Acetate (Standard diacetate; TFA-free) or Custom Options |
| Synthesis Technology | Solid-Phase Peptide Synthesis (SPPS) |
| Modification Options | C-terminal amidation (inherent), N-terminal modifications, isotope labeling |
| Available Scale | Milligram (R&D) to Kilogram (Commercial Manufacturing) |
| Analytical Data | Comprehensive COA, HPLC, MS provided per batch |
| Usage | Raw material synthesized strictly for laboratory research, cosmetic formulation R&D, and industrial manufacturing. Not a finished drug. |
Pentapeptide-3 (GPRPA-NH2, CAS 135679-88-8) is a synthetic pentamer featuring a C-terminal amide. We synthesize this specific sequence as a high-purity raw material for structural research and cosmetic formulation development.
We utilize optimized solid-phase peptide synthesis (SPPS). This platform ensures highly efficient amino acid coupling and precise control over deletion impurities, yielding batches that meet strict HPLC purity specifications.
Yes. While the standard Pentapeptide-3 sequence includes C-terminal amidation, our modification services can add targeted N-terminal protecting groups, specialized counter-ions, or isotopic labels to suit specific physical chemistry requirements.
Our infrastructure transitions seamlessly from milligram-scale laboratory batches to kilogram-scale commercial production. We maintain rigorous batch-to-batch consistency essential for industrial-scale formulation.
We serve as a strategic technical partner. Our team assists with sequence stability testing, impurity profiling, and the provision of complete analytical documentation to accelerate downstream formulation projects.
Pentapeptide-3, defined by the sequence GPRPA-NH2 and often referenced in cosmetic research as Vialox, is a short synthetic peptide. Synpeptide provides comprehensive synthetic solutions for this target molecule, leveraging our technical expertise to support industrial formulation development and cosmetic R&D.
Through our established peptide synthesis platform, we achieve efficient coupling of the pentamer sequence via optimized Solid-Phase Peptide Synthesis (SPPS). We strictly control impurity profiles and sequence deletions during manufacturing, ensuring the final Pentapeptide-3 material meets exact purity specifications (routinely ≥98% via HPLC). This rigorous process control guarantees the batch-to-batch reproducibility required for both early-stage research and late-stage commercial formulation.
The standard structure of Pentapeptide-3 requires a C-terminal amide. Beyond this baseline, we offer extensive peptide modification services. Formulators can request specific counter-ion exchanges (such as TFA to acetate conversions to yield the diacetate salt), targeted N-terminal modifications for altered solubility, or isotopic labeling for tracking studies. These structural adjustments enable researchers to precisely tune the molecule's physical properties for advanced delivery systems.
Scaling a peptide from benchtop research to commercial application demands stable manufacturing protocols. We facilitate efficient large-scale peptide synthesis for Pentapeptide-3, managing the transition from milligram screening batches to kilogram-scale production. Our large-scale infrastructure ensures a continuous, reliable supply chain for global cosmetic manufacturers, supported by complete analytical documentation including COA, MS, and HPLC data for every delivered batch.
We function as a technical extension of our clients' teams, providing one-stop peptide formulation support. Our engineers assist clients in stability testing, degradation profiling, and identifying optimal handling conditions for Pentapeptide-3 in various matrices. By delivering precise analytical data alongside high-purity synthetic capacity, we enable R&D teams to execute complex formulation projects efficiently and confidently.
