| Target Molecule | Palmitoyl Oligopeptide |
| Synonyms | Pal-VGVAPG, Palmitoyl Hexapeptide-12, Oligopeptide-34, Pal-Val-Gly-Val-Ala-Pro-Gly-OH |
| CAS Number | 171263-26-6 |
| Sequence (3-Letter) | Pal-Val-Gly-Val-Ala-Pro-Gly-OH |
| Sequence (1-Letter) | Pal-VGVAPG |
| Molecular Formula | C₃₈H₆₈N₆O₈ |
| Molecular Weight | 736.98 |
| Service Category | Custom Synthesis / Cosmetic Peptide R&D |
| Synthesis Purity | Customizable (e.g., ≥95%, ≥98%, ≥99% by HPLC) |
| Appearance | White to off-white powder |
| Counter Ion | Acetate (TFA-free available) or Custom Options |
| Synthesis Technology | Solid-Phase Peptide Synthesis (SPPS) |
| Modification Options | Alternate lipid conjugations, isotopic labeling, specific counter-ions |
| Available Scale | Milligram (R&D) to Kilogram (Commercial Manufacturing) |
| Analytical Data | Comprehensive COA, HPLC, MS provided per batch |
| Usage | Raw material synthesized strictly for laboratory research, cosmetic formulation R&D, and industrial manufacturing. Not a finished drug. |
Palmitoyl Oligopeptide (Pal-VGVAPG, CAS 171263-26-6) is a synthetic lipopeptide comprising an elastin-derived hexamer sequence conjugated with an N-terminal palmitic acid. We synthesize this specific target as a high-purity raw material for structural research and cosmetic formulation development.
We utilize optimized solid-phase peptide synthesis (SPPS). This platform ensures highly efficient amino acid coupling and precise control over deletion impurities, yielding batches that meet strict HPLC purity specifications.
Yes. The standard structure requires an N-terminal palmitic acid (C16 fatty acid) to confer lipophilicity. Our modification services can apply alternative lipid conjugates to fine-tune solubility, targeted isotopic labels, or specific counter-ions to suit varying physical chemistry requirements.
Our infrastructure transitions seamlessly from milligram-scale laboratory batches to kilogram-scale commercial production. We maintain rigorous batch-to-batch consistency essential for industrial-scale formulation.
We serve as a strategic technical partner. Our team assists with sequence stability testing, impurity profiling, and the provision of complete analytical documentation to accelerate downstream formulation projects.
Palmitoyl Oligopeptide, specifically the elastin-derived sequence Pal-VGVAPG (CAS 171263-26-6), is a widely utilized cosmetic lipopeptide. Synpeptide provides comprehensive synthetic solutions for this target molecule, leveraging our technical expertise to support industrial formulation development and cosmetic R&D.
Through our established peptide synthesis platform, we achieve efficient coupling of the hexamer sequence via optimized Solid-Phase Peptide Synthesis (SPPS). We strictly control impurity profiles during manufacturing, ensuring the final Palmitoyl Oligopeptide material meets exact purity specifications (routinely ≥95% via HPLC). This rigorous process control guarantees the batch-to-batch reproducibility required for both early-stage research and late-stage commercial formulation.
The core structural requirement of this lipopeptide is the attachment of palmitic acid to confer lipophilicity. Beyond this baseline, we offer extensive peptide modification services. Formulators can request specific counter-ion exchanges, alternate lipid conjugations to adjust solubility profiles for specific matrices (such as liposomal or glycol dispersions), or isotopic labeling for tracking studies. These structural adjustments enable researchers to precisely tune the molecule's physical properties for advanced delivery systems.
Scaling a lipopeptide from benchtop research to commercial application demands stable manufacturing protocols. We facilitate efficient large-scale peptide synthesis for Palmitoyl Oligopeptide, managing the transition from milligram screening batches to kilogram-scale production. Our large-scale infrastructure ensures a continuous, reliable supply chain for global cosmetic manufacturers, supported by complete analytical documentation including COA, MS, and HPLC data for every delivered batch.
We function as a technical extension of our clients' teams, providing one-stop peptide formulation support. Our engineers assist clients in stability testing, degradation profiling, and identifying optimal handling conditions for Palmitoyl Oligopeptide in various cosmetic bases. By delivering precise analytical data alongside high-purity synthetic capacity, we enable R&D teams to execute complex formulation projects efficiently and confidently.
