| Product Name | Hexapeptide-11 (Peptamide 6) |
| Synonyms | Peptamide 6, FVAPFP, Phe-Val-Ala-Pro-Phe-Pro, H-Phe-Val-Ala-Pro-Phe-Pro-OH |
| CAS Number | 100684-36-4 (also reported: 161258-30-6) |
| Sequence (3-Letter) | H-Phe-Val-Ala-Pro-Phe-Pro-OH |
| Sequence (1-Letter) | FVAPFP |
| Molecular Formula | C₃₆H₄₈N₆O₇ |
| Molecular Weight | 676.8 |
| Category | Cosmetic Peptide |
| Purity | ≥98% (by HPLC) |
| Appearance | White to off-white powder |
| Counter Ion | Acetate (TFA-free available on request) |
| Peptide Content | ≥90% |
| Solubility | Soluble in water |
| Storage | -20°C, desiccated, protected from light |
| Available Scale | mg – kg |
| QC Documentation | COA, HPLC, MS (included with every order) |
| Usage | For cosmetic formulation and research use only. Supplied as a raw material; finished-product efficacy and safety claims are the formulator's responsibility. Not a drug; not for direct use without formulation. |
Hexapeptide-11 is a cosmetic anti-aging peptide, also known by the trade name Peptamide 6, with the sequence Phe-Val-Ala-Pro-Phe-Pro (FVAPFP, CAS 100684-36-4). The sequence was originally identified in baker's yeast proteins and is now made by synthesis. It is supplied as a white powder for skincare and research.
It is used in anti-aging products to support the look of firmer, more elastic skin and to reduce the appearance of fine lines. Suppliers describe it as helping skin cells make more of their own collagen and elastin. Any efficacy claim on a finished product is the formulator's responsibility.
Hexapeptide-11 is a signal-type peptide. In laboratory studies on skin fibroblasts it is reported to support the cell's own stress-response and housekeeping pathways and to encourage the production of collagen and elastin, the proteins that give skin its firmness and bounce. Supporting that activity is the rationale for its firming, smoothing effect on the look of the skin. This is a cosmetic effect on the appearance of skin.
Hexapeptide-11 is water-soluble and is added to leave-on serums, creams, and lotions at low levels, commonly from a fraction of a percent up to a few percent. It pairs well with other anti-aging peptides. We can advise on use levels for your product.
Yes. We manufacture Hexapeptide-11 in-house and supply from milligrams to kilograms, with COA, HPLC, and MS included. Contact us with your required purity and quantity for a quote.
Hexapeptide-11 is a peptide used in anti-aging skincare to support firmer, more elastic skin and soften the look of fine lines. It is sold under the trade name Peptamide 6 and is a signal-type peptide that works with the skin's own cells rather than on muscle movement.
It is a six-amino-acid peptide with the sequence Phe-Val-Ala-Pro-Phe-Pro (FVAPFP). The sequence was first identified in proteins of baker's yeast, including stress-related proteins, and is now produced by solid-phase synthesis to high purity. Its CAS number is 100684-36-4, its molecular formula is C36H48N6O7, and its molecular weight is about 676.8.
Hexapeptide-11 is a signal-type peptide that works on skin fibroblasts, the cells that build the skin's support proteins. In laboratory studies it is reported to support the cell's own stress-response and housekeeping pathways and to encourage the production of collagen and elastin, the proteins behind skin firmness and bounce. Supporting that activity is the rationale for using it to firm and smooth the look of aging skin. The effect is on the appearance of the skin.
Hexapeptide-11 is water-soluble and is added at low levels to leave-on serums, creams, and lotions, commonly from a fraction of a percent up to a few percent. It is often paired with other anti-aging peptides, such as the collagen-supporting palmitoyl oligopeptide, for a broader effect on the look of firmness and fine lines. As with all cosmetic actives, any claim made on the finished product is the responsibility of the formulator.
Hexapeptide-11 is used at low levels and is handled as a standard cosmetic raw material. Supplier studies report improvement in the look of firmness, elasticity, and fine lines with regular use, but any claim on a finished product is the responsibility of the formulator, and finished products should be safety-assessed for their specific formula and use.
We manufacture Hexapeptide-11 by solid-phase synthesis and supply it from milligram to kilogram scale with a COA, HPLC, and MS report. For related ingredients and the underlying chemistry, see cosmetic peptides and custom peptide synthesis. This material is supplied for cosmetic formulation and research use and is not a drug.
