| Target Molecule | Hexapeptide-11 (Peptamide 6) |
| Synonyms | Peptamide 6, FVAPFP, Phe-Val-Ala-Pro-Phe-Pro, H-Phe-Val-Ala-Pro-Phe-Pro-OH |
| CAS Number | 100684-36-4 (also reported: 161258-30-6) |
| Sequence (3-Letter) | H-Phe-Val-Ala-Pro-Phe-Pro-OH |
| Sequence (1-Letter) | FVAPFP |
| Molecular Formula | C₃₆H₄₈N₆O₇ |
| Molecular Weight | 676.8 |
| Service Category | Custom Synthesis / Cosmetic Peptide R&D |
| Synthesis Purity | Customizable (e.g., ≥95%, ≥98%, ≥99% by HPLC) |
| Appearance | White to off-white lyophilized powder |
| Counter Ion | Acetate, TFA, or Custom Salt Options |
| Synthesis Technology | Solid-Phase Peptide Synthesis (SPPS) / Liquid-Phase Synthesis |
| Modification Options | N-terminal acetylation, C-terminal amidation, lipid conjugation, etc. |
| Available Scale | Milligram (R&D) to Kilogram (Commercial Manufacturing) |
| Analytical Data | Comprehensive COA, HPLC, MS provided per batch |
| Usage | Raw material synthesized strictly for laboratory research, cosmetic formulation R&D, and industrial manufacturing. Not a finished drug. |
Hexapeptide-11 (Phe-Val-Ala-Pro-Phe-Pro, CAS 100684-36-4) is a hexamer peptide sequence extensively studied for its applications in structural biology and cosmetic formulations. We utilize this specific molecule as a primary target for custom synthesis, supplying highly pure reference compounds and raw materials for advanced R&D projects.
We employ optimized solid-phase peptide synthesis (SPPS) methodologies. Our peptide synthesis platform ensures high-efficiency amino acid coupling and strict control over deletion sequences, resulting in superior purity and high-yield synthesis runs tailored to specific client specifications.
Yes. We offer comprehensive peptide modification services for the FVAPFP sequence. Options include N-terminal protection (such as acetylation or palmitoylation), C-terminal amidation, and the incorporation of stable isotopes or unnatural amino acids to meet specific stability or delivery requirements.
Our infrastructure supports seamless scaling from milligram-level lab batches to kilogram-level commercial manufacturing. We maintain rigorous batch-to-batch consistency and high purity profiles suitable for large-scale industrial formulation.
We act as a strategic partner providing one-stop peptide drug discovery and formulation support. Our technical team assists clients with sequence optimization, stability testing, impurity profiling, and the analytical documentation required to accelerate downstream project timelines.
Hexapeptide-11 (Peptamide 6), defined by the sequence FVAPFP, is a signal peptide widely utilized in cosmetic formulations. Synpeptide provides comprehensive synthetic solutions for this molecule, leveraging our technical expertise to support structural research, formulation development, and therapeutic R&D.
Utilizing our robust peptide synthesis platform, we achieve highly efficient coupling for the hexamer sequence via optimized Solid-Phase Peptide Synthesis (SPPS). We strictly control impurity profiles during the synthesis process, ensuring the final Hexapeptide-11 material meets stringent purity requirements (typically ≥98% via HPLC). This methodological rigor guarantees precise batch reproducibility, providing reliable raw materials for subsequent research and commercial formulation stages.
To meet specific physicochemical or bioavailability requirements in target formulations, we offer extensive peptide modification services. For the Hexapeptide-11 sequence, these modifications can include N-terminal protecting groups (e.g., palmitoylation or acetylation), C-terminal amidation, and the targeted incorporation of unnatural amino acids. These targeted structural alterations are critical for researchers evaluating structure-activity relationships or optimizing the peptide for advanced dermal delivery systems.
Transitioning a molecule from the laboratory bench to commercial application requires robust manufacturing processes. We facilitate seamless large-scale peptide synthesis for Hexapeptide-11, transitioning efficiently from initial milligram screening quantities to kilogram-scale commercial production. Our large-scale manufacturing infrastructure ensures a stable, consistent supply chain for cosmetic manufacturers and pharmaceutical developers, accompanied by complete analytical documentation including COA, MS, and HPLC data.
Beyond raw material manufacturing, we serve as a technical partner for one-stop peptide drug discovery. We actively assist clients in sequence optimization, stability assessments, and the identification of synthetic impurities. Whether integrating Hexapeptide-11 into dermatological research or developing novel cosmetic active formulations, our engineering team provides the precise analytical data and synthetic capacity required to execute complex R&D projects efficiently.
