| Target Molecule | H-Val-Trp-OH (Dipeptide-2) |
| Synonyms | Dipeptide-2, Val-Trp, L-Valyl-L-tryptophan, N-Valyltryptophan, VW |
| CAS Number | 24587-37-9 |
| Sequence (3-Letter) | H-Val-Trp-OH |
| Sequence (1-Letter) | VW |
| Molecular Formula | C₁₆H₂₁N₃O₃ |
| Molecular Weight | 303.36 |
| Service Category | Custom Synthesis / Cosmetic Peptide R&D |
| Synthesis Purity | Customizable (e.g., ≥95%, ≥98%, ≥99% by HPLC) |
| Appearance | White to off-white powder |
| Counter Ion | Free base / acetate (TFA-free available) or Custom Options |
| Synthesis Technology | Solid-Phase Peptide Synthesis (SPPS) / Liquid-Phase Synthesis |
| Modification Options | Isotopic labeling, specific counter-ions, alternate terminal protections |
| Available Scale | Milligram (R&D) to Kilogram (Commercial Manufacturing) |
| Analytical Data | Comprehensive COA, HPLC, MS provided per batch |
| Usage | Raw material synthesized strictly for laboratory research, cosmetic formulation R&D, and industrial manufacturing. Not a finished drug. |
Dipeptide-2 (H-Val-Trp-OH, CAS 24587-37-9) is a simple bioactive peptide comprising L-valine and L-tryptophan linked by a single peptide bond, retaining free N- and C-termini. We synthesize this specific sequence as a high-purity raw material for structural research and cosmetic formulation development.
Depending on the required scale, we utilize optimized solid-phase peptide synthesis (SPPS) or liquid-phase synthesis methodologies. These platforms ensure highly efficient amino acid coupling and precise control over related impurities, yielding batches that meet strict HPLC purity specifications.
Yes. While the standard structure features free termini, our modification services can add targeted isotopic labels, specific counter-ions (such as TFA to acetate conversions), or alternate terminal protections to suit specific physical chemistry requirements for advanced R&D.
Our infrastructure transitions seamlessly from milligram-scale laboratory batches to kilogram-scale commercial production. We maintain rigorous batch-to-batch consistency essential for industrial-scale cosmetic formulation.
We serve as a strategic technical partner. Our team assists with sequence stability testing, impurity profiling, and the provision of complete analytical documentation to accelerate downstream formulation projects.
Dipeptide-2, defined by the sequence H-Val-Trp-OH, is a widely utilized cosmetic dipeptide. Synpeptide provides comprehensive synthetic solutions for this target molecule, leveraging our technical expertise to support industrial formulation development and cosmetic R&D.
Through our established peptide synthesis platform, we achieve efficient coupling of the valyl-tryptophan sequence via optimized Solid-Phase Peptide Synthesis (SPPS) or liquid-phase techniques. We strictly control impurity profiles during manufacturing, ensuring the final Dipeptide-2 material meets exact purity specifications (routinely ≥98% via HPLC). This rigorous process control guarantees the batch-to-batch reproducibility required for both early-stage research and late-stage commercial formulation.
The baseline structure of Dipeptide-2 features free N- and C-termini. Beyond these standard parameters, we offer extensive peptide modification services. Formulators can request specific counter-ion exchanges to adjust solubility profiles, targeted isotopic labeling for tracking studies, or alternate terminal modifications. These structural adjustments enable researchers to precisely tune the molecule's physical properties for advanced delivery systems.
Scaling a peptide from benchtop research to commercial application demands stable manufacturing protocols. We facilitate efficient large-scale peptide synthesis for Dipeptide-2, managing the transition from milligram screening batches to kilogram-scale production. Our large-scale infrastructure ensures a continuous, reliable supply chain for global cosmetic manufacturers, supported by complete analytical documentation including COA, MS, and HPLC data for every delivered batch.
We function as a technical extension of our clients' teams, providing one-stop peptide formulation support. Our engineers assist clients in stability testing, degradation profiling, and identifying optimal handling conditions for Dipeptide-2 in various matrices. By delivering precise analytical data alongside high-purity synthetic capacity, we enable R&D teams to execute complex formulation projects efficiently and confidently.